Role of NK cells and adaptive immunity in “immunoediting”: Recent developments
نویسنده
چکیده
El papel de los distintos brazos del Sistema Inmune en el control y la eliminación de tumores ha sido objeto de un interés creciente. En este trabajo se discuten, en el marco de la teoría de la “inmunoedición”, una serie de datos recientes acerca del papel de la inmunidad en el control de los tumores. En particular, se comentan los datos de Guerra y cols acerca del papel de las células NK en la eliminación de tumores espontáneos en modelos transgénicos de tumorigénesis (Guerra y cols, 2008), y el notable trabajo de Koebel y cols (2007) en el que se muestra el papel de la inmunidad adaptativa en el mantenimiento como una enfermedad crónica de los tumores inducidos por agentes químicos.
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